Located 14 minutes' walk from MUSA - Museo Storico-Archeologico dell'Universita del Salento, 2 Santi Apartment Lecce hotel is approximately a 5-minute drive from Church of Saint Matthew.

The bed & breakfast lies in Old Town, which is renowned for the baroque style that characterizes portals, churches, spires, monuments and houses, a few minutes' drive from Centro Storico. The nearby places of worship include Lecce Cathedral (400 metres) and Chiesa della Nativita della Vergine Church (0.8 km). Basilica of Santa Croce is just 0.7 km from this Lecce hotel. The accommodation is located 50 km from Casale airport and within easy walking distance of Porta San Biagio bus stop.

The rooms come with coffee and tea making facilities, as well as a flat-screen TV with satellite channels for guests' convenience. Nice touches include a separate toilet and a shower, along with hair dryers and bath sheets.

Serving both food and drinks, Ristorante Via Cairoli is situated just near this hotel.